Governments will change, people on the top might change. The question is whether they will face any consequences for their actions. Will the US as a whole face any consequence of its actions. Like the consequences other countries face when they do the stuff America is doing right now.
Or will it be back to normal as soon as the regime changes.
Will there be any lasting effects in how the world deals with US?
Not until it becomes weaker militarily and economically is this a possibility or if the American population actually does something (unlikely near term).